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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
30
Human Site:
S345
Identified Species:
60
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
S345
K
Q
E
E
A
R
K
S
P
T
P
S
A
P
V
Chimpanzee
Pan troglodytes
XP_511742
777
85768
S345
K
Q
E
E
A
R
K
S
P
T
P
S
A
P
V
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
S345
K
Q
E
E
A
R
K
S
P
T
P
S
A
P
V
Dog
Lupus familis
XP_540486
782
86005
S349
K
Q
E
E
A
R
K
S
P
T
P
S
A
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
S345
K
Q
E
E
A
R
K
S
P
T
P
S
A
P
V
Rat
Rattus norvegicus
Q9JJ50
776
86228
S345
K
Q
E
E
A
R
K
S
P
T
P
S
A
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
S345
K
Q
E
E
V
R
K
S
P
T
P
S
A
P
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
S343
R
K
I
S
E
S
S
S
M
A
S
P
S
A
P
Honey Bee
Apis mellifera
XP_393989
830
92147
S344
Q
S
A
L
E
E
H
S
S
R
A
D
V
T
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
S342
S
L
P
Q
Y
S
Q
S
K
T
F
E
A
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
R247
S
K
K
H
R
H
K
R
K
K
D
R
D
Y
S
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
A342
E
Q
K
K
R
H
A
A
A
L
K
E
Q
T
S
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
26.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
50
0
9
9
9
9
9
0
67
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
9
9
0
0
% D
% Glu:
9
0
59
59
17
9
0
0
0
0
0
17
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
17
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
59
17
17
9
0
0
67
0
17
9
9
0
0
0
0
% K
% Leu:
0
9
0
9
0
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
9
0
0
0
0
0
59
0
59
9
0
59
9
% P
% Gln:
9
67
0
9
0
0
9
0
0
0
0
0
9
9
0
% Q
% Arg:
9
0
0
0
17
59
0
9
0
9
0
9
0
0
0
% R
% Ser:
17
9
0
9
0
17
9
84
9
0
9
59
9
0
25
% S
% Thr:
0
0
0
0
0
0
0
0
0
67
0
0
0
17
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _